View and download FRα and ovarian cancer resources

TAP TO DOWNLOAD PDF REFERENCES ON OVARIAN CANCER BIOMARKERS AND FRα IHC
FRα=folate receptor alpha; IHC=immunohistochemistry.
TAP TO DOWNLOAD PDF REFERENCES ON OVARIAN CANCER BIOMARKERS AND FRα IHC
Ovarian Cancer Information
FRα IHC Staining Assessment Summary
Summary of Challenging FRα Staining Patterns
FRα=folate receptor alpha; IHC=immunohistochemistry.
TAP TO VIEW
The role of FRα in cancer biology
FRα=folate receptor alpha; FOLR1=folate receptor 1.
References
  1. Bax HJ, Chauhan J, Stavraka C, et al. Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes. Br J Cancer. 2023;128(2):342-353. doi:10.1038/s41416-022-02031-x.
  2. Cheung A, Bax HJ, Josephs DH, et al. Targeting folate receptor alpha for cancer treatment. Oncotarget. 2016;7(32):52553-52574. doi:10.18632/oncotarget.9651.
  3. Mai J, Wu L, Yang L, et al. Therapeutic strategies targeting folate receptor α for ovarian cancer. Front Immunol. 2023;14:1254532. doi:10.3389/fimmu.2023.1254532.
  4. Birrer MJ, Betella I, Martin LP, Moore KN. Is targeting the folate receptor in ovarian cancer coming of age? Oncologist. 2019;24(4):425-429. doi:10.1634/theoncologist.2018-0459.
  1. Scaranti M, Cojocaru E, Banerjee S, Banerji U. Exploiting the folate receptor α in oncology. Nat Rev Clin Oncol. 2020;17(6):349-359. doi:10.1038/s41571-020-0339-5.
  2. Kalli KR, Oberg AL, Keeney GL, et al. Folate receptor alpha as a tumor target in epithelial ovarian cancer. Gynecol Oncol. 2008;108(3):619-626.doi:10.1016/j.ygyno.2007.11.020.
  3. Chen YL, Chang MC, Huang CY, et al. Serous ovarian carcinoma patients with high alpha-folate receptor had reducing survival and cytotoxic chemo-response. Mol Oncol. 2012;6:360-369. doi:10.1017/j.molonc.2011.11.010.